This product was formerly named Nanotrap® Magnetic Virus Particles.

Nanotrap® Microbiome Particles

Nanotrap Microbiome Particles rapidly concentrate microbes from many sample types, eliminating the need for filtration precipitation or centrifugation.

Large-scale wastewater surveillance can be used to help communities monitor infection dynamics for SARS-CoV-2 and other microbes of concern. Robust, high-throughput methods based on Nanotrap Microbiome Particles are enabling widespread implementation. 

  • Nanotrap particles utilize affinity capture and enrichment to attract and bind low abundance viruses.
  • Methods developed for clinical swab samples, saliva, urine, wastewater, food wash and blackwater.
  • Compatible with PCR, sequencing or immunoassay analysis methods.
  • Successfully utilized in high-complexity and point-of-care RT-PCR assays with FDA Emergency Use Authorization for COVID-19.
  • Nanotrap particles do not utilize antibodies or other biomolecules as affinity molecules, which means extended room temperature stability.
Ceres Nanotrap Microbiome A & B bottles

For Research Use Only. Not for use in diagnostic procedures.

Nanotrap Products​

Nanotrap Microbiome A Particles

The Nanotrap Microbiome A Particles have a broad affinity for a wide range of microbes and can capture and concentrate influenza A, influenza B, respiratory syncytial virus, coronavirus 229E, coronavirus OC43, SARS-CoV-2, Zika virus, Chikungunya virus, dengue virus, pepper mild mottle virus, hepatitis A virus and mpox virus.

Nanotrap Microbiome B Particles

The Nanotrap Microbiome B Particles have been demonstrated to capture and concentrate a wide range of microbes, including Escherichia coli, Salmonella enterica, Campylobacter jejuni, Listeria monocytogenes, Clostridioides difficile and crASSphage.

Nanotrap Enhancement Reagents​

Nanotrap Microbiome Particles rapidly capture and concentrate microbes from raw sewage requiring no filtration or centrifugation. Using Nanotrap Enhancement Reagents with the Nanotrap particles improves the binding of microbes in these samples, further improving downstream detection of nucleic acids.

Nanotrap Buffer 2

Nanotrap Buffer 2 improves microbe recovery with Ceres Nanotrap Microbiome Particles when using a manual method. Nanotrap Buffer 2 homogenizes solids, dilutes viscous samples and facilitates movement of Nanotrap Microbiome Particles between tubes.

Ordering Information

A growing list of microbes have been captured and concentrated with the Nanotrap Microbiome Particles. If you don’t see the microbe of interest on this list, please contact us to discuss your application.


  • Designed to capture and concentrate a variety of microbes.
  • Provide a simple and rapid approach for concentration of microbes from various sample types.
  • Utilize affinity capture and enrichment technology to bind low abundance targets.
  • Wastewater processing protocols are available for manual or automated workflows.


Sample processing time comparison

PEG Precipitation sample process timeline
Nanotrap Microbiome Particles sample process timeline
DescriptionCatalog Number
Nanotrap Microbiome A Particles 10 mL Vial250068
Nanotrap Microbiome A Particles 30 mL Vial250069
Nanotrap Microbiome B Particles 10 mL Vial250075
Nanotrap Microbiome B Particles 30 mL Vial250076
Nanotrap Enhancement Reagent 1 (ER1) 10 mL250070
Nanotrap Enhancement Reagent 2 (ER2) 10 mL250071
Nanotrap Enhancement Reagent 3 (ER3) 10 mL250077
Nanotrap Buffer 2 100 mL250081
Nanotrap Enhancement Reagent 1 (ER1) 30 mL250072
Nanotrap Enhancement Reagent 2 (ER2) 30 mL250073
Nanotrap Enhancement Reagent 3 (ER3) 30 mL250078


Order Nanotrap Microbiome Particles today

New customers

Existing customers

International customers find a distributor


Wastewater Manual Protocol


Wastewater Auto Protocol

Tech Note 880239 - Improved methodology for detection of antibiotic resistance mechanisms from wastewater for population surveillance

Technical Note

Combining Nanotrap Particle-based capture and concentration with qPCR analysis using the Streck ARM-D Kits creates a consistent and reliable protocol for wastewater AMR surveillance.

Read the Tech Note
What Lies Beneath: Wastewater Testing for Pathogens

What Lies Beneath: Wastewater Testing for Pathogens

Dr. Michael Wiley discusses the wastewater surveillance program in Nebraska and describes how wastewater-based epidemiology can protect communities from future outbreaks.

Watch the webinar
Member of the University of Massachusetts, Amherst SARS-CoV-2wastewater surveillance team
UMass Amherst school logo

How Nanotrap Technology for Wastewater Surveillance Improves SARS-CoV-2 Workflows

Read the interview
University of Nevada, Reno school logo

How Nanotrap Particle Technology is Improving the Public Health Response to SARS-CoV-2

Read the interview

Nanotrap Microbiome Particles compatibility across different nucleic acid extraction kits


Extraction Kit 



Nanotrap Microbiome A

Nanotrap Microbiome B

Enhancement Reagent 1

Enhancement Reagent 2

Enhancement Reagent 3


NucleoMag DNA/RNA Water Kit




Applied Biosystems™

MagMAX™ Viral/Pathogen Nucleic Acid Extraction Kit




Applied Biosystems™

MagMAX™ Viral/Pathogen II (MVP II) Nucleic Acid Extraction Kit




Applied Biosystems™

MagMAX™ Microbiome Ultra Nucleic Acid Kit





MagAttract® Viral RNA Kit (960)





QIAamp® Viral RNA Mini Kit (250)





AllPrep® PowerViral® DNA/RNA Kit (50)




Zymo Research





Maxwell® HT Environmental TNA Kit, Custom




Water DNA/RNA Magnetic Bead Kit



All trademarks are the property of their respective owners


APP-075 R01 Automated Nanotrap Microbiome A and B Enviro Water Protocol using MagMAX Kit_10 mL
APP-090 R00 Nanotrap Microbiome Combined_ 10mL Manual Protocol with AllPrep PowerViral DNA RNA Mini Kit
APP-098 R00 Nanotrap Microbiome A 10mL Automated Protocol with MagMAX Kit and KingFisher Flex

View all protocols


Molecular Diagnostics (MDx) are the tests and techniques that have been developed in recent decades that analyze biological markers such as nucleic acids and proteins, to diagnose and monitor disease, detect disease risks and to monitor the effectiveness of treatments. MDx assays are used in prenatal testing, infectious disease testing, cancer and inherited diseases testing.

Streck ARM-D Kits

The latest from the blog


Webinar: What Lies Beneath: Wastewater Testing for Pathogens

Wastewater-based epidemiology (WBE) is a powerful tool for monitoring the emergence of infectious pathogens. While WBE has been around since the 1800s…
Read More
Wastewater sample testing

WBE: Which method is fastest?

Sample processing for measuring SARS-CoV-2 RNA in wastewater involves sample preparation, sample concentration, RNA extraction and RNA measurement met…
Read More

Preventing infections in dialysis patients

A recent report published by the Centers for Disease Control and Prevention outlines the challenges faced by 800,000 people in the United States who a…
Read More