Sickle Cell Screening
Hemoglobin S and Sickle Cell
Sickle cell is a condition in which red blood cells become rigid and sickle shaped. Sickled cells have less oxygen carrying capability and may have a shorter life than normal blood. Not only does this condition impact patient health but also impacts facilities such as blood banks, which need to ensure their supply of normal blood. Screening for Hemoglobin S is an effective indicator that the blood carries the sickle cell trait.
Sickle Cell Screening at Your Fingertips
Globally, the number of individuals living with sickle cell disease is roughly 7.74 million, an increase of about 41% from 5.46 million in 2000.1 Having a screening test that does not require any instrumentation is critical, as sickle cell disease tends to impact less developed areas that have limited access to modern health care. Further, blood banks can benefit from effective testing that does not require any instrumentation.
1. GBD 2021 Sickle Cell Disease Collaborators. Global, regional, and national prevalence and mortality burden of sickle cell disease, 2000–2021. The Lancet Haematology, June 2023. View the study →
Where QC Creates Value
To ensure the results of sickle cell screening, it is best practice to perform quality control to help ensure patient results that may be compromised during the test preparation process. Errors may occur during the reconstitution step, or the solution may have been compromised due to environmental factors.
Complete Sickle Cell Testing Solution
Meet all of your sickle cell testing needs by combining SICKLEDEX® Hemoglobin S solubility testing with Sickle-Chex® quality control. SICKLEDEX is an easy-to-use Hemoglobin S solubility testing kit that requires only 20 µL of patient sample and is packaged with two separate squeeze bottles for easy dispensing and elimination of waste. Sickle-Chex is ready to use and is packaged in squeeze dropper vials to eliminate the need for pipetting.
Products
IVD · FDA Cleared
IVD · FDA ClearedCE-IVD
SICKLEDEX®
Solubility screening kit validated across eight anticoagulants. No pipetting, results in as little as 6 minutes.
IVD · FDA Cleared
IVD · FDA ClearedCE-IVD
Sickle-Chex®
Positive and negative whole blood control. No reconstitution or pipetting, in squeeze dropper vials, handled like a patient sample.
Resources
IFU
Instructions for Use
Current package inserts, the sickle test protocol template and certificates of conformance by lot.
Application
Sickle Cell Trait Testing in Athletes
Why sickle cell trait screening has become standard practice in athletic programs, and what a result changes.
Guidance
APHL and CDC Hemoglobinopathy Testing
Current practices for screening, confirmation and follow-up, including the limits of solubility testing.
FAQ
Top Questions About SICKLEDEX
Anticoagulant compatibility, kit configurations, read times and the role of the control, answered in one place.
Partner With Streck
Leading instrument manufacturers partner with Streck to provide their customers with dependable third-party quality controls. Streck is the leader in cell stabilization for over 50 years and continues to manufacture and develop high performing controls.
- Sophisticated R&D to rapidly develop products
- Advanced QC, with barcoded solutions and included ILQC program for increased value
- Highly trained technical and sales support
