SEARCH
The Streck ARM-D Kit, β-Lactamase is a multiplex real-time PCR kit for the rapid detection of β-lactam antibiotic resistance genes in Gram-negative bacteria. This comprehensive kit allows you to detect over 450 allelic variants in 9 clinically relevant carbapenemases, extended-spectrum beta-lactamases (ESBLs) and plasmid-mediated ampC gene families, KPC, NDM, OXA-48, IMP, VIM, DHA, CMY-2, CTX-M-14 and CTX-M-15.
Every kit includes positive controls for each gene target to monitor analytical process as well as an endogenous internal control (16SrRNA gene) to reduce false negatives due to PCR inhibition, DNA degradation or poor extraction.
All Streck ARM-D kits are compatible with most 4-channel real-time thermal cyclers. An amplification protocol and analysis guide are available for the following instruments: Applied Biosystems™ 7500 Fast and 7500 Fast Dx, QuantStudio™ 7Flex, Bio-Rad CFX96 Touch™ and QIAGEN Rotor-Gene® Q.
For Research Use Only. Not for use in diagnostic procedures.
Detects over 450 allelic variants in the KPC, NDM, OXA-48, IMP, VIM, DHA, CMY-2, CTX-M-14 and CTX-M-15 gene families
Compatible with most 4-channel real-time PCR thermal cyclers
Protocol can be completed in less than one hour
Contains positive controls for each gene target
Includes a premixed 2X master mix (DNA Polymerase, dNTPs, MgCl2 and reaction buffer)
Detects gene variants not covered by cartridge-based kits
Identifies resistance mechanisms before susceptibility results are available
High degree of sensitivity and specificity ensures reliable and accurate results
Reduced cost per sample compared to cartridge-based methods
| Description | Item Number |
|---|---|
| Streck ARM-D Kit, β-Lactamase RUO | 250045 |
The ARM-D Kit, β-Lactamase is a multiplex real-time PCR kit for the rapid detection of β-lactam antibiotic resistance genes in gram-negative bacteria. This comprehensive kit detects over 450 allelic variants in 9 clinically relevant gene families: carbapenemases (KPC, NDM, OXA-48, IMP, VIM), extended-spectrum beta-lactamases (CTX-M-14, CTX-M-15) and plasmid-mediated ampC genes (DHA, CMY-2).
Streck ARM-D Kits are for Research Use Only (RUO) and are not for use in diagnostic procedures.
The ARM-D Kit, β-Lactamase detects over 450 allelic variants across 9 gene families, including the most clinically significant carbapenemases (KPC, NDM, OXA-48, IMP, VIM), extended-spectrum beta-lactamases (CTX-M-14, CTX-M-15) and plasmid-mediated ampC genes (DHA, CMY-2).
Carbapenemases are enzymes that break down carbapenem antibiotics, which are often considered last-line treatments for multidrug-resistant infections. Early detection of carbapenemase genes (KPC, NDM, OXA-48, IMP, VIM) is critical for implementing appropriate infection control measures, guiding antibiotic therapy and preventing the spread of highly resistant organisms in healthcare settings.
The ARM-D Kit, β-Lactamase is compatible with most 4-channel real-time PCR thermal cyclers. This broad compatibility allows laboratories to implement the kit using their existing molecular testing platforms.
The ARM-D Kit, β-Lactamase provides rapid detection of resistance mechanisms, allowing laboratories to improve surveillance, aid antibiotic stewardship programs and support infection control programs. By identifying specific resistance genes, the kit helps implement targeted infection prevention strategies, reducing inappropriate antibiotic use and limiting the spread of resistant organisms.
Powered by Bioz