Cyto-Chex® BCT

Cyto-Chex BCT is a direct draw blood collection tube that maintains cellular morphology and surface antigen expression, including cluster of differentiation (CD) markers, prior to analysis by flow cytometry. It is FDA 510(k) cleared for consistent recovery of HIV-associated lymphocyte subsets (CD3, CD4, CD8, CD19, CD16/CD56 and CD45) for up to 14 days of room temperature storage.

Whole blood samples collected in Cyto-Chex BCT can be stored at room temperature for up to 14 days while maintaining cellular integrity and CD marker expression. This extended stability allows for flexible scheduling of flow cytometry analysis and eliminates the need for immediate sample processing.

Yes, Cyto-Chex BCT has been FDA 510(k) cleared for consistent recovery of HIV-associated lymphocyte subsets (CD3, CD4, CD8, CD19, CD16/CD56 and CD45) for up to 14 days. This clearance provides assurance of quality and performance for laboratories performing HIV monitoring and other immunophenotyping applications.

Cyto-Chex BCT limits the adverse effects of time, storage and transport conditions on sample integrity, reducing the likelihood of sample degradation that could require patient recalls. The 14-day room temperature stability provides ample time for sample transport and analysis, even from remote collection sites, minimizing the need for repeat blood draws and associated costs.

Cyto-Chex BCT is available in both 5 mL and 2 mL vials, providing flexibility for different sample volume requirements. The smaller 2 mL size is particularly useful for pediatric patients or situations where minimizing blood draw volume is important.

Yes, Cyto-Chex BCT allows for the batching of samples, optimizing laboratory workflow. The extended 14-day stability at room temperature reduces the need for immediate sample processing and enables laboratories to accumulate samples for more efficient batch analysis by flow cytometry.

Flow cytometry testing traditionally requires same-day analysis because white blood cells rapidly degrade and lose surface marker expression in standard blood collection tubes. This creates scheduling challenges for laboratories and access barriers for patients at remote locations. Cyto-Chex BCT’s room temperature stabilization maintains cellular morphology and CD marker expression for up to 14 days, enabling flexible testing schedules, centralized testing models and improved access to specialized flow cytometry services without compromising result quality.

Cyto-Chex BCT prevents the time-dependent cellular changes that normally occur in whole blood after collection. By limiting the adverse effects of time, storage and transport conditions on sample integrity, Cyto-Chex BCT ensures that flow cytometry results reflect the patient’s true cellular profile at the time of blood draw rather than artifacts of sample aging.