MDx-Chex® for RLP

MDx-Chex for RLP is a full-process molecular quality control designed to support research, development, optimization, verification and analytical performance assessment of laboratory assays targeting respiratory pathogens including Influenza A, Influenza B, Human Rhinovirus, Human Respiratory Syncytial Virus (RSV), SARS-CoV-2 and S. pyogenes (Group A Strep). Each control contains intact, inactivated microorganisms suspended in a stabilized, patient-like matrix of blood cells and epithelial cells to evaluate the entire molecular testing process, from extraction to detection.

No, MDx-Chex for RLP is for Research Use Only and not for use in diagnostic procedures. This control is intended for research applications, assay development, optimization, verification and analytical performance assessment of respiratory pathogen molecular testing workflows.

MDx-Chex for RLP includes six key respiratory pathogens: Influenza A, Influenza B, Human Rhinovirus, Human Respiratory Syncytial Virus (RSV), SARS-CoV-2 and S. pyogenes (Group Strep A). This comprehensive panel covers the most clinically significant respiratory pathogens commonly tested in multiplex molecular assays. We recommend that you verify that control target coverage is adequate for your sample-to-result system of choice.

MDx-Chex for RLP is platform agnostic, meaning it has been verified on multiple molecular diagnostics platforms and is not limited to a single manufacturer’s system. This flexibility allows researchers and assay developers to use the same control across different testing platforms during development, optimization and verification studies without needing to purchase platform-specific controls.

MDx-Chex for RLP contains a patient-like matrix of inactivated microorganisms, blood cells and epithelial cells that mimics actual respiratory specimens. This composition challenges the entire molecular testing workflow including sample preparation, lysis, nucleic acid extraction and detection, ensuring that quality control evaluates the complete procedure as it would be performed on real patient samples rather than only testing the detection step.

Yes, MDx-Chex for RLP can be stored at room temperature. This room temperature stability eliminates the need for freezer storage, prevents freeze-thaw cycles that can damage nucleic acids and organism integrity and simplifies logistics for research laboratories conducting validation studies or assay development work.

Single-use vials reduce preanalytical variables such as pipetting errors and cross-contamination that can occur with multi-use controls. Each vial provides a fresh, uncontaminated sample that ensures consistent quality control performance and eliminates concerns about contamination between uses or degradation from repeated freeze-thaw cycles, which is particularly important when validating assays for multiple respiratory pathogens.

MDx-Chex for RLP offers a simplified workflow: simply mix the vial contents, pipette the control like a patient sample, scan the barcode if applicable and run the assay. This ease of use makes the control practical for frequent testing during assay development, optimization and verification studies without adding complexity to laboratory workflows.