MDx-Chex® for MVP

MDx-Chex for MVP is a full-process molecular quality control designed for the comprehensive validation of molecular assays that identify vaginitis-causing bacteria. Each control contains intact, inactivated microorganisms suspended in a stabilized, patient-like matrix of red blood cells and epithelial cells to evaluate the entire molecular testing process, from extraction to detection.

No, MDx-Chex for MVP is for Research Use Only and not for use in diagnostic procedures. This control is intended for research applications and validation of molecular assay workflows that detect vaginitis-causing pathogens.

Vaginitis is inflammation of the vagina that can be caused by various microorganisms including bacteria, yeast and parasites. MDx-Chex for MVP is designed for validation of molecular assays that identify Bacterial vaginosis, Candida group, Candida-glab-krus and Trichomonas vaginalis. We recommend verifying that control target coverage is adequate for your specific sample-to-results system of choice.

MDx-Chex for MVP contains a patient-like matrix of inactivated microorganisms, red blood cells and epithelial cells that mimics actual vaginal specimens. This composition challenges the entire molecular testing workflow including sample preparation, nucleic acid extraction and detection, providing realistic quality control that evaluates the complete procedure as it would be performed on real patient samples.

Yes, MDx-Chex for MVP can be directly used on sample-to-answer platforms and with multiple assays. However, we recommend that you verify that control target coverage is adequate for your sample-to-results system of choice before implementing the control in your workflow.

MDx-Chex for MVP is supplied in single-use vials with room temperature stability. The single-use format eliminates concerns about contamination or degradation after opening, while room temperature stability eliminates freeze-thaw cycles that can degrade nucleic acids and compromise control performance.

MDx-Chex for MVP uses pooled targets in a single control formulation, meaning multiple vaginitis-causing bacteria are present in one vial. This reduces the number of cartridges or test runs needed per control session compared to running separate controls for each pathogen, saving time and reducing costs in validation workflows.

Single-use vials reduce preanalytical variables such as pipetting errors and cross-contamination that can occur with multi-use controls. Each vial provides a fresh, uncontaminated sample that can be pipetted directly like a patient sample, ensuring consistent quality control performance and eliminating concerns about contamination between uses or degradation from repeated freeze-thaw cycles.

Room temperature stability eliminates the need for freezer storage and eliminates freeze-thaw cycles that can damage nucleic acids and affect organism integrity. This simplifies storage requirements, improves convenience for validation studies and ensures that control performance remains consistent throughout the product’s shelf life without the logistical challenges of maintaining frozen storage.